Molecular Testing & Oncology

Molecular Testing Services

Tulsa Medical Laboratory offers a state of the art in house molecular department that focuses on women’s health testing. The Hologic Thin Prep Pap Test has proven to be the perfect media for performing molecular testing which enables the clinicians to obtain six results with one sample collection; cytology, chlamydia, gonorrhea, trichomonas vaginalis, high risk HPV and genotyping for HPV 16 and 18/45. A single one milliliter aliquot can be tested up to six times.

Molecular Testing Staff

Currently Tulsa Medical Lab offers testing for Chlamydia trachomatis, Neisseria Gonorrhea, Trichomonas vaginalis, High Risk HPV, HPV Genotyping of HPV 16 and 18/45 directly from the Thin Prep Pap test vial. In addition HSV 1 & 2 is available from the Aptima Multi test swab. Trichomonas and Chlamydia and Gonorrhea can also be tested for from the Aptima Multi test swab.

Complete automation of molecular testing is achieved by utilizing the Hologic Tomcat for transfer of the barcoded specimen from the thin prep vial to the Aptima Specimen Transport Tube. The Aptima Specimen Transport tubes are then placed on the Hologic Panther. The Hologic Panther is a random access, fully automated system that performs all the Aptima Assays that Tulsa Medical Laboratory offers. The Panther was recently upgraded to include a fluorometer which enables it to perform real time assays in addition to end point assays. End point assays take 3.5 hours to yield the first result; real time assays yield result in 2.7 hours.

Both types of assays employ the proven Aptima technology of target capture and target amplification by transcription Mediated Amplification. The assays differ in the method of detection; the end point assays utilize HPA (Hybridization Protection Assay) and a luminometer for determining the RLU’s (relative light units) of each sample. The real time assays utilize a fluorometer and fluorescent labeled probes referred to as “torches” in detecting the amplicon along with an internal control to monitor targeted nucleic acid capture, amplification and detection.

For additional information on our current testing options please contact the molecular department at (918) 481-7857.

Oncology Testing

Tulsa Medical Laboratory realizes the need for comprehensive tumor profiles and targeted biomarker tests that lead to the best possible treatment modality for each individual patient. We work with a CAP and CLIA certified national laboratory to expediently provide this information.

KRAS, BRAF, EGFR, NGS and PD-L1 testing are performed by the Saint Francis Hospital Laboratory. A wide variety of immunohistochemistry, fluorescence in situ hybridization (FISH) tests, and flow cytometry are also available. Our experienced, knowledgeable pathology staff is available to answer questions and share their vast wealth of experience with you.

For more information, please call us at (918) 481-7859.